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There is no such thing as a simple miracle.
Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to "awaken" the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial treatment. His awakening, filled with awe and enthusiasm, proves a rebirth for Sayer too, as the exuberant patient reveals life's simple but unutterably sweet pleasures to the introverted doctor.
Robert De Niro
Leonard Lowe
Robin Williams
Malcolm Sayer
John Heard
Dr. Kaufman
Julie Kavner
Eleanor Costello
Penelope Ann Miller
Paula
Ruth Nelson
Mrs. Lowe
Max von Sydow
Peter Ingham
Anne Meara
Miriam
Dexter Gordon
Rolando
George Martin
Frank
Alice Drummond
Lucy Fishman
Richard Libertini
Sidney
Laura Esterman
Lolly
Barton Heyman
Bert
Judith Malina
Rose
Mary Alice
Nurse Margaret
Keith Diamond
Anthony
Bradley Whitford
Dr. Tyler
John Christopher Jones
Dr. Sullivan
Le Clanché du Rand
Magda
Yusef Bulos
Joseph
Steven Randazzo
Luis
Steve Vinovich
Ray
Tiger Haynes
Janitor
Peter Stormare
Neurochemist
Charles Keating
Mr. Kean
Mel Gorham
Nurse Sara
Bret McCormick
Head Ward Orderly
Gordon Joseph Weiss
Ward #5 Patient
Byron Utley
Ward #5 Patient #2
Vincent Pastore
Ward #5 Patient #6
Harry L. Seddon
Medical Student
Jack Mulcahy
Psych Ward Intern
Vin Diesel
Hospital Orderly (uncredited)